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Indigenous peoples, probably of Asian descent, have inhabited what is now the mainland United States for many thousands of years. This Native American population was greatly reduced after European contact by disease and warfare. The United States was founded by thirteen British colonies located along the Atlantic seaboard. On July 4, 1776, they issued the Declaration of Independence, which proclaimed their right to self-determination and their establishment of a cooperative union. The rebellious states defeated Great Britain in the American Revolutionary War, the first successful colonial war of independence. The Philadelphia Convention adopted the current United States Constitution on September 17, 1787; its ratification the following year made the states part of a single republic with a strong central government. The Bill of Rights, comprising ten constitutional amendments guaranteeing many fundamental civil rights and freedoms, was ratified in 1791.
At 3.79 million square miles (9.83 million km2) and with about 308 million people, the United States is the third or fourth largest country by total area, and the third largest by land area and population. It is one of the world's most ethnically diverse and multicultural nations, the product of large-scale immigration from many countries. The U.S. economy is the largest national economy in the world, with an estimated 2008 gross domestic product (GDP) of US $14.4 trillion (a quarter of nominal global GDP and a fifth of global GDP at purchasing power parity).